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Gluscosamine/Chondroitin JBJS

First posted October 23, 2001 Last updated July 19, 2005

This article is from the Journal of Bone & Joint Surgery. It is written for orthopedic surgeons, so it may be a bit hard to follow. If you would like to read it, it is available for purchase from the JBJS or you can read it at the MGH Medical Library (925-7393). I wanted to provide this reference so that you have more information upon which to make your decisions, and felt that the opinions expressed in the offical orthopedic journal have special weight. I know the first author; he is a straight shooter. - Dr. Nelson

From Lemons and Oranges to Glucosamin and Chondroitine Sulfate: Clinical Observation Stimulates Basic Research

The Orthopedic Forum
(from the Journal of Bone & Joint Surgery, Volume 83, Number 8)

Joseph A. Buckwalter, MD, John J. Callaghan, MD and Randy N. Rosier, MD, PhD
Joseph A. Buckwalter, MD
John J. Callaghan, MD
Department of Orthopaedic Surgery, University of Iowa College of Medicine, 01008 Pappajohn Pavilion, Iowa City, IA 52242.
E-mail address for J.A. Buckwalter: joseph-buckwalter@uiowa.edu
Randy N. Rosier, MD, PhD
Department of Orthopaedics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, P.O. Box 665,
Rochester, NY 14642

This article examines some of the evidence for the effectiveness of oral glucosamine and chondroitin sulfate. There is little to no evidence that there is a physiologic explanation for their effectiveness, poor quality support for clinical evidence for their effectiveness, but enough suggestive evidence that further research is a good idea. ~Dr. Nelson